Division of Biostatistics and Bioinformatics

About Us

Founded in 1997, the Division of Biostatistics of the National Health Research Institutes was the first academic biostatistics institution in Taiwan. It's aim is the advancement of Taiwan biomedical and health research. Due to the growing importance of bioinformatics in the genomic Research at NHRI, starting from December of 2000, the Division is now the Division of Biostatistics and Bioinformatics.

Under the leadership of Dr. Chao Agnes Hsiung, the Division endeavors to advance biostatistics methodological research and theory, to assist in intramural collaborative research in statistical design and analysis, to develop and maintain the NHRI biomedical research data management system, to support biostatistics and bioinformatics related research for intramural and extramural projects, to promote information exchange and communication among biostatistical researchers in Taiwan and abroad, and to provide necessary biostatistics and bioinformatics consultation and educational training for biomedical researchers.


The mission of the Division of Biostatistics and Bioinformatics (DBB) is to apply statistical knowledge and informatics technology to promote and improve human health and welfare in Taiwan.

DBB works toward this mission by:

Research Projects

Clinical Trials


TCOG is the sole group in Taiwan that conducts multi-center trials. The Statistical Center of TCOG was established at the outset when TCOG launched in 1989. The Statistical Center is now located in the Division of Biostatistics and Bioinformatics, National Health Research Institutes and in charge of both the data management and statistical support for all clinical trials conducted by TCOG.

The Statistical Center initiated the "Data Safety and Monitoring Committee" which is responsible for monitoring the safety and ethics of trials during their process. The statistical center also initiated the "Audit Committee" to ensure the data quality of the trial.

Nowadays, TCOG also conducts some other trials different from previous research. For example, the longitudinal follow-up study entitled "A multi-center survey of HPV in cervical intraepithelial neoplasia (CIN) with longitudinal follow-up of LSIL cases" has a different point of view in statistical consideration.

Besides cancer clinical trials, the Division of Biostatistics also supports other NHRI divisions and Department of Health, the Exective Yuan in conducting other clinical research and the regulation of clinical trials.

The study status of all clinical trials conducted by TCOG is listed as the following:

1.Current Studies

2. Proposed studies

3. Terminated studies