National Institute of Cancer Research
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Research Programs
On-Going Programs in 2008
- Study on the mechanism of modulation of DNA repair enzyme, O6-methylguanine DNA methyltransferase, in human cancer cells
- A study of the mechanisms of oxaliplatin resistance in a human gastric carcinoma cell line
- Mobilization of Bone Marrow Stem Cells and Cancer Cells by Granulocyte Colony-Stimulating Factor in Cancer Therapy
- The Role of mTOR Inhibition in Cancer Therapy
- The Effects of Hepatitis B Virus X Protein to the Bone-Marrow Derived Mesenchymal Stem Cells (MSC) and MSC Trans-differentiated Hepatocytes
- Study on the interactions among tumor metastasis-related proteins and its application in cancer therapy
- Molecular dissection of ENO1-induced immunosuppression in cancer patients
- Isolate Active Ingredients Targeting Cancer Stem Cells from CDA-2–A Novel Multimolecular Targeting AntiCancer Agent and Study the Underlying Mechanisms
- Study of AXL promoter and a possible negative feedback auto-regulation mechanism
- Mechanisms for Macrophage-Induced Tumor Cell Spreading and Drug Resistance
- Studies of factors affecting sensitivity to chemotherapeutic nucleoside analogs
- The role of Cdc25 protein phosphatases in the G2 checkpoint activated by protein-damaging stress
- A genomic screen for hypermethylation genes and their functional roles in human metastasis cancers
- Role of Cited2, a novel transcriptional co-activator, in lung cancer progression
- Effects of Reactivation of Epstein-Barr Virus Latent Infection on the Genomic Instability in Nasopharyngeal Carcinoma Cells
- Development of Microarray Collaborative Lab and Study on the Normalization and Analysis of Microarray-based CGH Data
- Study the modulation of TIEG1 in cellular apoptosis
- Study of human PREPL and KLK13 serine protease genes in cancer development and malignancy
- KSHV Reactivation in KS Pathogenesis
- Development of Molecular Targeted Therapy for Advanced Gastric Cancers -- emphasis on the studies of PI3K/AKT/mTOR pathway, VEGF/VEGFR angiogenesis pathway, and EGFR/MAPK pathway
- Study on the Modulation of Nrf2/ARE Pathway in Chemoprevention, Cancer Development and Chemoresistance
- Mechanisms Study of Receptor Tyrosine Kinase Axl’s Signaling Pathways in MMPs Secretion and Tumor Invasion)
- Program project on tumor metastasis-Cross-class interaction between cathepsin cysteine proteases and metastasis-suppressing SERPINB serine protease inhibitors
- Role of imbalance between metastasis-related proteases and protease inhibitor in lung cancer development and malignancy
- National Cinical Trial Research Network